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Das Bild zeigt rechts ein Trichterglas mit blauer Flüssigkeit und Glasstab zum Umrühren. Daneben steht ein Reagenzglasständer mit Reagenzgläsern, die ebenfalls blaue Flüssigkeit enthalten. Im Hintergrund ist ein Forscher zu sehen, der in der rechten Hand eine Pipette hält.

Selected Publications

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Selected Publications

Epifanova, E., V. Salina, D. Lajko, K. Textoris-Taube, T. Naumann, O. Bormuth, I. Bormuth, S. Horan, T. Schaub, E. Borisova, M.C. Ambrozkiewicz, V. Tarabykin, and M. Rosario. 2021. Adhesion dynamics in the neocortex determine the start of migration and the post-migratory orientation of neurons. Sci Adv. 7.

Parthasarathy, S., S. Srivatsa, A.I. Weber, N. Graber, O.V. Britanova, E. Borisova, P. Bessa, M.C. Ambrozkiewicz, M. Rosario, and V. Tarabykin. 2021. TrkC-T1, the Non-Catalytic Isoform of TrkC, Governs Neocortical Progenitor Fate Specification by Inhibition of MAP Kinase Signaling. Cereb Cortex. 31:5470-5486.

Ambrozkiewicz, M.C., E. Borisova, M. Schwark, S. Ripamonti, T. Schaub, A. Smorodchenko, A.I. Weber, H.J. Rhee, B. Altas, R. Yilmaz, S. Mueller, L. Piepkorn, S.T. Horan, R. Straussberg, S. Zaqout, O. Jahn, E. Dere, M. Rosario, P. Boehm-Sturm, G. Borck, K.I. Willig, J. Rhee, V. Tarabykin, and H. Kawabe. 2020. The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc. Mol Psychiatry. April 6.

Ambrozkiewicz, M.C., M. Schwark, M. Kishimoto-Suga, E. Borisova, K. Hori, A. Salazar-Lazaro, A. Rusanova, B. Altas, L. Piepkorn, P. Bessa, T. Schaub, X. Zhang, T. Rabe, S. Ripamonti, M. Rosario, H. Akiyama, O. Jahn, T. Kobayashi, M. Hoshino, V. Tarabykin, and H. Kawabe. 2018. Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140. Neuron. 100:1097-1115 e1015.

Schuster, S., M. Rivalan, U. Strauss, L. Stoenica, T. Trimbuch, N. Rademacher, S. Parthasarathy, D. Lajko, C. Rosenmund, S.A. Shoichet, Y. Winter, V. Tarabykin, and M. Rosario. 2015. NOMA-GAP/ARHGAP33 regulates synapse development and autistic-like behavior in the mouse. Mol Psychiatry. 20:1120-1131.

Rosario, M., S. Schuster, R. Juttner, S. Parthasarathy, V. Tarabykin, and W. Birchmeier. 2012. Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin. Genes Dev. 26:1743-1757.

Grossmann, K.S., M. Rosario, C. Birchmeier, and W. Birchmeier. 2010. The tyrosine phosphatase Shp2 in development and cancer. Adv Cancer Res. 106:53-89.

Hellmuth, K., S. Grosskopf, C.T. Lum, M. Wurtele, N. Roder, J.P. von Kries, M. Rosario, J. Rademann, and W. Birchmeier. 2008. Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking. Proc Natl Acad Sci U S A. 105:7275-7280.

Rosario, M., R. Franke, C. Bednarski, and W. Birchmeier. 2007. The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42. J Cell Biol. 178:503-516.

Schaeper, U., R. Vogel, J. Chmielowiec, J. Huelsken, M. Rosario, and W. Birchmeier. 2007. Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo. Proc Natl Acad Sci U S A. 104:15376-15381.

Brembeck, F.H., M. Rosario, and W. Birchmeier. 2006. Balancing cell adhesion and Wnt signaling, the key role of beta-catenin. Curr Opin Genet Dev. 16:51-59.

Rosario, M., and W. Birchmeier. 2004. Making tubes: step by step. Dev Cell. 7:3-5.

Schuetz, G., M. Rosario, J. Grimm, T.M. Boeckers, E.D. Gundelfinger, and W. Birchmeier. 2004. The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells. J Cell Biol. 167:945-952.

Rosario, M., and W. Birchmeier. 2003. How to make tubes: signaling by the Met receptor tyrosine kinase. Trends Cell Biol. 13:328-335.

Rosario, M., H.F. Paterson, and C.J. Marshall. 2001. Activation of the Ral and phosphatidylinositol 3' kinase signaling pathways by the ras-related protein TC21. Mol Cell Biol. 21:3750-3762.

Rosario, M., H.F. Paterson, and C.J. Marshall. 1999. Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells. EMBO J. 18:1270-1279.

Barnett, S.C., M. Rosario, A. Doyle, A. Kilbey, A. Lovatt, and D.A. Gillespie. 1995. Differential regulation of AP-1 and novel TRE-specific DNA-binding complexes during differentiation of oligodendrocyte-type-2-astrocyte (O-2A) progenitor cells. Development. 121:3969-3977.