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Selected Publications

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Selected Publications

Ire1α-Regulated Rate of mRNA Translation is Required for Acquisition of Identity and Polarity in Upper Layer Cortical Neurons
Mateusz C. Ambrozkiewicz, Ekaterina Borisova, Andrew G. Newman, Matthew L. Kraushar, Theres Schaub, Rike Dannenberg, Marisa Brockmann, Marta Rosário, Paul Turko, Olaf Jahn, David R. Kaplan, Takao Iwawaki, Christian M. T. Spahn, Christian Rosenmund, Victor Tarabykin, doi: doi.org/10.1101/2021.06.23.449563

Timed global reorganization of protein synthesis during neocortex neurogenesis at codon resolution
Dermot Harnett, Mateusz C. Ambrozkiewicz, Ulrike Zinnall, Ekaterina Borisova, Alexandra Rusanova, Rike Dannenberg, Koshi Imami, Agnieszka Münster-Wandowski, Beatrix Fauler, Thorsten Mielke, Matthias Selbach, Markus Landthaler, Christian M.T. Spahn, Victor Tarabykin, Uwe Ohler, Matthew L. Kraushar, doi: doi.org/10.1101/2021.06.23.449626

Molecular Evolution, Neurodevelopmental Roles and Clinical Significance of HECT-Type UBE3 E3 Ubiquitin Ligases.
Ambrozkiewicz MC, Cuthill KJ, Harnett D, Kawabe H, Tarabykin V. Cells. 2020 Nov 10;9(11):2455. doi: 10.3390/cells9112455. PMID: 33182779

The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc.
Ambrozkiewicz MC, Borisova E, Schwark M, Ripamonti S, Schaub T, Smorodchenko A, Weber AI, Rhee HJ, Altas B, Yilmaz R, Mueller S, Piepkorn L, Horan ST, Straussberg R, Zaqout S, Jahn O, Dere E, Rosário M, Boehm-Sturm P, Borck G, Willig KI, Rhee J, Tarabykin V, Kawabe H. Mol Psychiatry. 2021 Jun;26(6):1980-1995. doi: 10.1038/s41380-020-0714-8. Epub 2020 Apr 6. PMID: 32249816

Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140.
Ambrozkiewicz MC, Schwark M, Kishimoto-Suga M, Borisova E, Hori K, Salazar-Lázaro A, Rusanova A, Altas B, Piepkorn L, Bessa P, Schaub T, Zhang X, Rabe T, Ripamonti S, Rosário M, Akiyama H, Jahn O, Kobayashi T, Hoshino M, Tarabykin V, Kawabe H. Neuron. 2018 Dec 5;100(5):1097-1115.e15. doi: 10.1016/j.neuron.2018.10.008. Epub 2018 Nov 1. PMID: 30392800